Determination of the Serum Osteocrin Concentration by a New ELISA Method

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  • D. Stejskal Department of Laboratory Medicine.Hospital, Šternberk,
  • M. Švesták Department of Laboratory Medicine.Hospital, Šternberk,
  • H. Kotolová Veterinary Faculty, Brno, Czech Republic,
  • M. Karpíšek Veterinary Faculty, Brno, Czech Republic,
  • K. Adamcová Gnosis Ltd., Slovak Republic
  • L. Sporová Department of Laboratory Medicine.Hospital, Šternberk,
  • P. Hejduk Department of Laboratory Medicine.Hospital, Šternberk,

Abstrakt

The osteocrin (musculin) concentration in blood serum was recently identified as a parameter of energetic homeostasis and bone modulation. At present, however, there are no valid data on osteocrin concentrations in serum and no routine method of its analysis in humans. The development and validation of a new ELISA method for osteocrin determination in serum and its testing in individuals with metabolic syndrome are described. It has been found that the osteocrin values are not able to differentiate between individuals with metabolic syndrome and controls. The serum osteocrine is probably not a useful marker for metabolic syndrome diagnosis.

Publikováno

15.12.2009

Jak citovat

Stejskal, D., Švesták, M., Kotolová, H., Karpíšek, M., Adamcová, K., Sporová, L., & Hejduk, P. (2009). Determination of the Serum Osteocrin Concentration by a New ELISA Method. Chemické Listy, 103(11). Získáno z http://ww.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/1441

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