Determination of Anti-Cathepsin-D Antibodies in Human Blood Sera of Oncological Patients

Autoři

  • I. Machová Department of Biochemistry and Microbiology, Institute of Chemical Technology, Prague,
  • J. Zídková Department of Biochemistry and Microbiology, Institute of Chemical Technology, Prague,
  • D. Springer Department of Clinical Biochemistry and Laboratory Medicine, First Faculty of Medicine, Charles University, Prague),
  • V. Větvička Department of Pathology, University of Louisville, Louisville, USA
  • M. Fusek Department of Biochemistry and Microbiology, Institute of Chemical Technology, Prague,

Abstrakt

In this study the levels of auto-antibodies formed against the activation peptide of procathepsin D were determined by the ELISA method using a synthetic multiantigen peptide containing the N-terminal amino acid sequence of the activation peptide of procathepsin D as a coating antigen. Based on the results auto-antibodies cannot be considered suitable cancer markers.

Publikováno

15.09.2012

Jak citovat

Machová, I., Zídková, J., Springer, D., Větvička, V., & Fusek, M. (2012). Determination of Anti-Cathepsin-D Antibodies in Human Blood Sera of Oncological Patients. Chemické Listy, 106(8). Získáno z http://ww.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/874

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