Dynamic in vivo ³¹P Magnetic Resonance Spectroscopy in Humans

Authors

  • M. Hájek MR-Unit, Department of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague
  • P. Šedivý MR-Unit, Department of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague | 1ˢᵗ Faculty of Medicine, Charles University in Prague, Prague
  • J. Kovář MR-Unit, Department of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague
  • M. Dezortová MR-Unit, Department of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague

Keywords:

in vivo dynamic ³¹P MR spectroscopy, muscular energy metabolism, pH, mitochondrial capacity

Abstract

The constructions of super high (3T) and ultra high field (7T) magnetic resonance (MR) imagers in the past decade have enabled many MR imaging and spectroscopy experiments with other nuclei than protons. The paper summarizes the basis of in vivo dynamic 31P MR spectroscopy for biomedical and clinical applications. The calculations of quantitative parameters of muscular metabolism, such as pH, mitochondrial capacity, ADP concentration, time constant of phosphocreatine recovery and others, are shown. The construction of ergometers for the whole body magnetic resonance systems is described. Examples of typical data processing and evaluation are demonstrated.

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Published

2017-08-15

How to Cite

Hájek, M., Šedivý, P., Kovář, J., & Dezortová, M. (2017). Dynamic in vivo ³¹P Magnetic Resonance Spectroscopy in Humans. Chemické Listy, 111(8), 516–523. Retrieved from http://ww.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/55

Issue

Vol. 111 No. 8 (2017)

Section

Articles