Capillary Electrochromatography

Abstract

Capillary electrochromatography (CEC) can be considered a hybrid of capillary electrophoresis and high performance liquid chromatography (HPLC). The growing interest in this technique is reflected in an increasing number of relevant scientific publications. CEC uses an electrically driven flow to transport the solutes through the chromatographic column. Separation can be achieved by differential interaction with stationary phase, differential electromigration, or a combination of both. The main features of CEC are presented, including basic principles and a literature overview on the practical approaches used.